Wong, V., Pearsall, D., Arriaga R., Ip, N.Y., Stahl N., and Lindsay, R.M. (1995)
Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines.
 J. Biol. Chem. 270: 313-318.
[Full text] [Full text]
Valenzuela, D.M., Rojas E., Le Beau, M.M., Espinosa III., R., Brannan, C.I., McClain, J., Masiakowski, P., Ip, N.Y., Copeland, N.G., Jenkins, N.A., and Yancopoulos, G.D. (1995)
Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. 
Genomics 25: 157-163.
[Abstract] [Full text]
Asada, H., Ip, N.Y., Pan, L., Razack, N., Parfitt, M.M., and Plunkett, R.J. (1995)
Time course of ciliary neurotrophic factor mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum. 
J. Neurosci. Res. 40: 22-30.
[Abstract]
Valenzuela, D.M., Rojas, E., Griffiths, J.A., Compton, D.L., Gisser, M., Ip, N.Y., Goldfarb, M., and Yancopoulos, G.D. (1995)
Identification of full-length and truncated forms of Ehk-3, a novel member of the Eph receptor tyrosine kinase family. 
Oncogene 10: 1573-1580.
Valenzuela, D.M., Economides, A.N., Rojas, E., Lamb, T.M., Nunes, L., Jones, P., Ip, N.Y., Espinosa, III, R., Brannan, C.I., Gilbert, D.J., Copeland, N.G., Jenkins, N.A., Le Beau, M.M., Harland, R.M., and Yancopoulos, G.D. (1995)
Identification of mammalian noggin and its expression in the adult nervous system.
J. Neurosci. 15: 6077-6084.
[Full text]
Friedman, B., Kleinfeld, D., Ip, N.Y., Verge, V.M., Moulton, R., Boland, P., Zlotchenko, E., Lindsay, R.M., and Liu, L. (1995)
BDNF and NT4/5 exert neurotrophic influences on injured adult spinal motor neurons. 
J. Neurosci. 15: 1044-1056.
[Full text]
Waraksa, J.A., Lindsay, R.M., Ip, N.Y., and Hutz, R.J. (1995)
Neurotrophin-3 augments steroid secretion by hamster ovarian follicles 
in vitro. Zool. Sci. 12: 499-502.
[Full text]
Conover, J.C., Erickson, J.T., Katz, D.M., Bianchi, L.M., Poueymirou, W.T., McClain, J., Pan, L., Helgren, M., Ip, N.Y., Boland, P., Friedman, B., Weigand, S., Vejsada, R., Kato, A., DeChiara, T.M., and Yancopoulos, G.D. (1995)
Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. 
Nature 375: 235-238.
[Abstract]
DeChiara, T.M., Vejsada, R., Pouyemirou, W.T., Acheson, A., Suri, C., Conover, J.C., McClain, J., Pan, L., Stahl, N., Ip, N.Y., Kato, A., and Yancopoulos, G.D. (1995)
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. 
Cell 83: 313-322.
[Abstract] [Full text]
Ip, F.C.F., Fu, A.K.Y., Tsim, K.W.K., and Ip, N.Y. (1995)
Cloning of the a component of the chick ciliary neurotrophic factor receptor: developmental expression and downregulation in denervated skeletal muscle. 
J. Neurochem. 65: 2393-2400.
[Abstract]
Stahl, N., Boulton, T. G., Farruggella, T., Ip, N.Y., Davis, S., Witthuhn, B., Quelle, F. W., Silvennoinen, O., Barbieri, G., Pellegrini, S., Ihle, J. N., and Yancopoulos, G.D. (1994)
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. 
Science 263: 92-95.
[Abstract]
Hyman, C., Juhasz, M., Jackson, C., Wright, P., Ip, N.Y., and Lindsay, R.M. (1994)
Overlapping and distinct actions of the neurotrophins, BDNF, NT-3 and NT-4/5, on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. 
J. Neurosci.14: 335-347.
[Full text]
Curtis, R., Scherer, S.S., Somogyi, R., Adryan, K.M., Ip, N.Y., Zhu, Y., Lindsay, R.M., and DiStefano, P.S. (1994)
Retrograde axonal transport of LIF is increased by peripheral nerve injury: Correlation with increased LIF expression in distal nerve. 
Neuron 12: 191-204.
[Abstract]
Thaler, C., Suhr, L., Ip, N. Y., and Katz, D. (1994)
Leukemia inhibitory factor and neurotrophins support overlapping populations of rat nodose sensory neurons in culture. 
Developmental Biology 161: 338-344.
[Abstract]
Rudge, J.S., Li, Y., Pasnikowski, E.M., Mattsson, K., Pan, L., Yancopoulos, G.D., Wiegand, S.J., Lindsay, R.M., and Ip, N.Y. (1994)
Neurotrophic factor receptors and their signal transduction capabilities in astrocytes. 
Eur. J. Neurosci. 6: 693-705.
[Abstract]
Stahl, N., Boulton, T.G., Ip, N.Y., Davis, S., and Yancopoulos, G.D. (1994)
The tails of two proteins: the scrapie prion protein and the ciliary neurotrophic factor receptor. 
Brazilian J. Med. Biol. Res. 27: 297-301.
Verdi, J.M., Ip, N.Y., Yancopoulos, G.D., and Anderson, D.J. (1994)
Expression of p140 trk in MAH cells lacking p75LNGFR is sufficient to permit NGF-induced differentiation to post-mitotic neurons. 
Proc. Natl. Acad. Sci. USA 91: 3949-3953.
[Full text]
Ip, N.Y., Boulton, T.G., Li, Y., Verdi, J.M., Birren, S.J., Anderson, D.J., and Yancopoulos, G.D. (1994)
CNTF, FGF and NGF collaborate to drive the terminal differentiation of MAH cells into post-mitotic neurons.  
Neuron 13: 443-455.
[Abstract]
Altar, C.A., Siuciak, J.A., Wright, P., Lindsay, R.M., Ip, N.Y., and Wiegand, W.J. (1994)
In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]-NT-3. 
Eur. J. Neurosci. 6: 1389-1405.
[Abstract]
Ip, N.Y. (1994)
Neurotrophic factors collaborate to drive differentiation of neuronal progenitor cells. 
Neurosci. Lett. 45: 52.
Glass, D.J., Gies, D.R., Stitt, T.N., Davis, S., Hantzopoulos, P., Ip, N.Y., Goldfarb, M., and Yancopoulos, G.D. (1993)
Cloning and analysis of neurotrophic factor receptors using function-based strategies. 
Cold Spring Harbor Symposia on Quantitative Biology 57: 53-62.
Wong, V., Arriaga, R., Ip, N.Y., and Lindsay, R.M. (1993)
The neurotrophins BDNF, NT-3, and NT-4, but not NGF, up-regulate the cholinergic phenotypic of developing motor neurons. 
Eur. J. Neurosci 5: 466-474.
[Abstract]
Davis, S., Aldrich, T.H., Ip, N.Y., Stahl, N., Scherer, S., Farruggella, T., DiStefano, P., Curtis, R., Panayotatos, N., Gascan, H., Chevalier, S., and Yancopoulos, G.D. (1993)
Released form of CNTF receptor α component as a soluble mediator of CNTF responses. 
Science 259: 1736-1739.
[Abstract]
Ip, N.Y., Morse, J.K., Wiegand, S.J., and Rudge, J.S. (1993)
Injury-induced regulation of CNTF mRNA in the adult rat brain. 
Eur. J. Neurosci. 5: 25-33.
[Abstract]
Ip, N.Y., McClain, J., Barrezueta, N., Aldrich, T.H., Pan, L., Li, Y., Wiegand, S.J., Friedman, B., Davis, S., and Yancopoulos, G.D. (1993)
The α component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development.
Neuron 10: 89-102.
[Abstract]
Ip, N.Y., Stitt, T.N., Tapley, P., Klein, R., Glass, D.J., Fandl, J., Greene L.A., Barbacid, M., and Yancopoulos, G.D. (1993)
Similarities and differences in the way neurotrophins interact with the Trks in neuronal and nonneuronal cells. 
Neuron 10: 137-149.
[Abstract]
Ibanez, C.F., Ernfors, P., Timmusk, T., Ip, N.Y., Arenas, E., Yancopoulos, G.D., and Persson, H. (1993)
Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion. 
Development 117: 1345-1353.
[Full text]
Valenzuela, D.M., Maisonpierre, P.C., Glass, D.J., Rojas, E., Nunez, L., Kong, Y., Gies, D.R., Stitt, T.N., Ip, N.Y., and Yancopoulos, G.D. (1993)
Alternate forms of rat TrkC with different functional capabilities.
Neuron 10: 963-974.
[Abstract]
Stahl, N., Davis, D., Wong, V., Taga, T., Tadamitsu, K., Ip, N.Y., and Yancopoulos, G.D. (1993)
Crosslinking of CNTF and LIF to endogenous and reconstructed receptor complexes identifies LIF binding protein as a CNTF receptor component. 
J. Biol. Chem. 268: 7628-76.
[Abstract] [Full text]
Davis, S., Aldrich, T., Stahl, N., Pan L., Taga, T., Kishimoto, K., Ip, N.Y., and Yancopoulos, G.D. (1993)
LIFR β and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. 
Science 260: 1805-1808.
[Abstract]
Lohof, A.M., Ip, N.Y., and Poo, M.-m. (1993)
Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. 
Nature 363: 350-353.
[Abstract]
Ip, N.Y., Li, Y., Yancopoulos, G.D., and Lindsay, R.M. (1993)
Cultured hippocampal neurons show responses to BDNF, NT-3 and NT-4 but not NGF. 
J. Neurosci. 13: 3394-3405.
[Full text]
Conover, J.C., Ip, N.Y., Poueymirou, W.T., Bates, B., Goldfarb, M.P., DeChiara, T.M., and Yancopoulos, G.D. (1993)
Ciliary neurotrophic factor maintains pluripotentiality of embryonic stem cells. 
Development 119: 559-565.
[Abstract] [Full text]
Sofroniew, M.V., Cooper, J.D., Svendsen, C.N., Crossman, P., Ip, N.Y., Lindsay, R.M., Zafra, F., and Lindholm, D. (1993)
Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. 
J. Neurosci. 13: 5263-5276.
[Full text]
Ip, N.Y., Ibanez, C.F., Nye, S.H., McClain, J., Jones, P.F., Gies, D.R., Belluscio, L., Le Beau, M.M., Espinosa III, R., Squinto, S.P., Persson, H., and Yancopoulos, G.D. (1992)
Mammalian neurotrophin-4: Structure, chromosomal localization, tissue distribution and receptor specificity. 
Proc. Natl. Acad. Sci. 89: 3060-3064.
[Full text]
Rudge, J.S., Alderson, R.F., Pasnikowski, E., McClain, J., Ip, N.Y., and Lindsay, R.M. (1992)
Expression of ciliary neurotrophic factor and the neurotrophins - Nerve growth factor, brain derived neurotrophic factor and neurotropin3- in cultured rat hippocampal astrocytes. 
Eur. J. Neurosci., 4: 459-471.
[Abstract]
Nye, S.H., Squinto, S.P., Glass, D.J., Stitt, T.N., Hantzopoulos, P., Macchi, M.J., Lindsay, N.S.,Ip, N.Y., and Yancopoulos, G.D. (1992)
K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses.
Mol. Biol. Cell 3: 677-686.
[Abstract] [Full text]
Ip, N.Y., Nye, S.H., Boulton, T. G., Davis, S., Taga, T., Li, Y., Birren, S.J., Yasukawa, K., Kishimoto, T., Anderson, D.J., Stahl, N., and Yancopoulos, G.D. (1992)
CNTF and LIF act on neuronal cells via shared signalling pathways that involve the IL-6 signal transducing receptor component gp130. 
Cell 69: 1121-1132.
[Abstract]
Friedman, B., Scherer, S.S., Rudge, J.S., Helgren, M., Morrisey, D., McClain, J., Wang, D.-W., Wiegand, S.J., Furth, M.E., Lindsay, R.M. and Ip, N.Y. (1992)
Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo. 
Neuron 9: 295-305.
[Abstract]
Maisonpierre, P.C., Le Beau, M.M., Espinosa III, R., Ip, N.Y., Belluscio, L., de la Monte, S.M., Squinto, S., Furth, M.E., and Yancopoulos, G.D. (1991)
Human and rat BDNF and NT-3: Gene structures, distributions and chromosomal localizations. 
Genomics 10: 558-568.
[Abstract]
Boulton, T.G., Nye, S.H., Robbins, D.J., Ip, N.Y., Radziejewska, E., Morgenbesser, S.D., DePinho, R.A., Panayotatos, N., Cobb, M.H., and Yancopoulos, G.D. (1991)
Erks: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. 
Cell 65: 663-675.
[Abstract]
Lindsay, R.M., Alderson, R.F., Friedman, B., Hyman, C., Ip, N.Y., Furth, M.E., Maisonpierre, P.C., Squinto, S.P., and Yancopoulos, G.D. (1991)
The neurotrophin family of NGF-related neurotrophic factors. 
Restorative Neurology and Neuroscience 2: 211-220.
[Full text]
Ip, N.Y., Li, Y., van de Stadt, I., Panayotatos, N., Alderson, R.F., and Lindsay, R.M. (1991)
Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures. 
J. Neurosci. 11: 3124-3134.
[Full text]
Ip, N.Y., Maisonpierre, P., Alderson, R., Friedman, B., Furth, M.E.,  Panayotatos, N., Squinto, S., Yancopoulos, G.D., and Lindsay, R.M. (1991)
The neurotrophins and CNTF: Specificity of action towards PNS and CNS neurons. 
J. Physiol., Paris 85: 123-130.
 
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